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Effet de l'hydroxyurée sur les protéines d'adhésion des globules rouges et des cellules endothéliales chez les enfants drépanocytaires
Effect of hydroxyurea on adhesion proteins of red blood cells and endothelial cells in children with drepanocytemia
Studio in aperto, di fase II, per valutare la sicurezza, la tollerabilità, la farmacocinetica e gli effetti sulla concentrazione epatica di ferro di dosi ripetute da 10 mg8Kg/die di ICL 670 in pazienti pediatrici con B-talassemia major con necessità di trasfusioni ematiche
An open label, phase IIa study to evaluate the safety, tolerability, pharmacokinetics and the effects on liver iron concentration of repeated doses of 10 mg/Kg/day of ICL670 administered of pediatric patients with transfusion-dependent B-thalassemia major
Origine cellulaire et propriétés des microparticules dans la drépanocytose. Effet potentiel de l.hydroxyurée
Cellular origin and properties of the microparticles in the sickle cell disease. Potential effect of hydroxyurea
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