A randomised controlled trial of wet wrap therapy in the treatment of childhood atopic dermatitis
DEC-NET Serial number GB404
Published online23/05/2005 13.56.00
Last updated06/03/2006 17.40.59
Other protocol ID numberN0405128530
This trial has been approved by an ethics committee
Current trial statusOpen (actively recruiting new participants)
Major Disease
(ICD9 class)		Atopic dermatitis and related conditions
Experimental drug
Wet wrap therapy
Control drug
HYDROCORTISONE
GenderBoth
Age (range)under 5 years

Eligibility criteria
Inclusion criteria
suffering from atopic dermatitis
Exclusion criteria
children whom will not tolerate 'wet wrap' therapy

Trial design/methodology
Phase3
Kind of study
DesignControlled
Randomised
Purpose of study
to ascertain whether or not the use of Wet Wrap Therapy (WWT) is more effective than conventional therapy with topical hydrocortisone in the treatment of atopic dermatitis in preschool children.
Primary outcomes
To ascertain whether or not the use of Wet Wrap Therapy is more effective than conventional therapy with topical hydrocortisone.
Secondary outcomes
Reduction in signs and symptoms
Summary of study design, objectives, and ongoing research findings
An observational randomised controlled trial; to compare the cost effectiveness of using wet wrap therapy and topical hydrocrizone in the treatment of atopic dermatitis in children under the age of 5 years. Children will be randomised into one of three groups - group 1 receive 2 weeks WWT with Tubifast and once daily 1% hydrocortisone Group 2 - 2 weeks of twice daily 1% hydrocortisone without WWT group 3 - 2 weeks of emollients and WWT without 1% hydrocortisone
Principal investigator
NameDr Margaret Sue Lewis-Jones
InstitutionNinewells Hospital and Medical School
Postal addressDundee, DD1 9SY
CityDundee
CountryUNITED KINGDOM
Phone01382 660111
Fax01382 633901
E-mailsue.lewis-jones@tudht.scot.nhs.uk


Sponsor name
British Skin Foundation (Charity)

ISRCTN  EudraCT